Validation of a Cannabinoid Quantitation Method Using an Agilent 6430 LC/MS/MS Authors
نویسنده
چکیده
A method was developed and validated for the quantitation of cannabinoids with LC/MS/MS using an Agilent 6430 Triple Quadrupole LC/MS system. Validation showed that the LC/MS/MS method provides reliable results for the quantitation of THC, OH-THC, and carboxy-THC that meet predetermined acceptance criteria [1]. The concentration range of target compounds used in this validation was chosen to fit the commonly encountered range of analyte concentrations seen in casework. The method displays excellent accuracy and precision for the detection of cannabinoids in blood. Other aspects evaluated during validation include interference, stability, dilution integrity, suppression/enhancement, and recovery for all target compounds.
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تاریخ انتشار 2013